Non-invasive prediction of persistent villous atrophy in celiac disease

Chronic diarrhea because of villous atrophy unrelated to celiac disease.

A71-year-oldwomanwas admittedwith a 7-monthhistoryofwaterydiarrhea,which had led to an unintentional 30kg (27%) of weight loss and admittance to the intensive care unit (ICU) on two separate occasions as a result of dehydration. Endoscopy and video capsule evaluation revealed villous atrophy of the entire small bowel, with fissuring, nodularity, and loss of folds, as shown for both duodenum (●"...

[Non celiac villous atrophy: more confusion or a new syndrome?].

It is not unusual for clinicians, particularly for those working in gastroenterology, to find intestinal villus atrophy (IVA) in duodenum biopsies from patients treated with chronic diarrhoea. In most cases, this finding rules out the existence of coeliac disease (CD)1. CD is an autoimmune disease that mostly develops in genetically predisposed subjects carrying HLA-DQ2/DQ82. To obtain a defini...

Celiac disease: anti-endomysial antibody versus villous atrophy.

Recommendations to quantify villous atrophy in video capsule endoscopy images of celiac disease patients

AIM To quantify the presence of villous atrophy in endoscopic images for improved automation. METHODS There are two main categories of quantitative descriptors helpful to detect villous atrophy: (1) Statistical and (2) Syntactic. Statistical descriptors measure the small intestinal substrate in endoscope-acquired images based on mathematical methods. Texture is the most commonly used statisti...

Ethnic Variations in Duodenal Villous Atrophy Consistent With Celiac Disease in the United States.

BACKGROUND & AIMS Celiac disease is a common disorder with a worldwide distribution, although the prevalence among different ethnicities varies. We aimed to measure the prevalence of duodenal villous atrophy among patients of different ethnicities throughout the United States. METHODS We performed a cross-sectional study of all patients who had duodenal biopsies submitted to a national pathol...